4E Binding Protein 1, phosphorylated (Ser65) (Protein Synthesis Initiation Factor 4E Binding Protein, eIF-4EBP1, PHAS-1, PHAS-I, Eukaryotic Translation Initiation Factor BP), Rabbit

Produktübersicht

• Artikelname: 4E Binding Protein 1, phosphorylated (Ser65) (Protein Synthesis Initiation Factor 4E Binding Protein, eIF-4EBP1, PHAS-1, PHAS-I, Eukaryotic Translation Initiation Factor BP), Rabbit
• Artikelnummer: USB-0004-20
• Hersteller Artikelnummer: 0004-20
• Alternativnummer: USB-0004-20-100
• Hersteller: US Biological
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IP, WB
• Immunogen: Synthetic phosphopeptide derived from the sequence of mouse 4E-BP1.

Produktbeschreibung

4E-BP1 (also known as PHAS-1) normally binds eIF4E, inhibiting cap-dependent translation. Hyperphosphorylation of 4E-BP1 disrupts this binding, activating cap-dependent translation. The PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1. 4E-BP1

Produkteigenschaften

• UniProt: Q60876
• Reinheit: Purified by Protein A and peptide affinity chromatography.
• Formulierung: Supplied as a liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. No preservative added.