| Insecticide, nematocide. Coumaphos is useful in cannabis testing kits as a component of pesticide mixes. Coumaphos is an organophosphate pesticide.1 It is converted into an oxon-containing metabolite in vivo, similar to other organophosphate pesticides, that inhibits acetylcholinesterase. It is active against adult, but not arrested stage, O. ostertagi helminths. 2 Coumaphos is toxic to A. stephensi and A. aegypti mosquitoes when applied topically, with median lethal doses of 0.002 and 0.012ug per female mosquito, respectively, but not when used as a contact insecticide.3 It is lethal to rats (LD50s = 41 and 16mg/kg for male and female rats, respectively). 4 Formulations containing coumaphos have been used to control pests in livestock. Synonyms: O-(3-Chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-Diethyl Ester, 3-Chloro-4-methyl-7-coumarinyl Diethyl Phosphorothioate, Asuntol, Baymix, Muscotox, Resitox CAS No: 56-72-4 Molecular Formula: C14H16ClO5PS Molecular Weight: 362.77 Purity: 95% Melting Point: 93-95C Solubility: DMSO (Slightly), Methanol (Slightly) TLC Conditions: SiO2, Hexanes : Ethyl Acetate = 9 : 1, Visualized with UV, AMCS, and KMnO4, Single Spot, Rf = 0.30. Method for Determining Identity: Proton NMR, 31P NMR, and MS conform to structure. Elemental Analysis: Calculated: %C: 46.35, %H: 4.45 Appearance: Pale red to tan solid Storage and Stability: Store at -20C. Hygroscopic, Under Inert Atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |
