CP-100356 is a specific inhibitor of MDR1 (P-Gp), the protypical ABC transporter. CP-100356 also inhibits prazosin transport in human breast cancer resistance protein (BCRP)-transfected MDCKII cells, suggesting that it acts as a dual inhibitor. CP-100356 does not inhibit multidrug resistance-associated protein 2 (MPR2 IC50 >15 mM). Form: Off-White to Light Tan Solid Melting Point: 210-212C Solubility: Chloroform, Methanol Pfizer Compound
Molekulargewicht:
597.1
Formulierung:
Off-White to Light Tan Solid
CAS Nummer:
[142715-48-8]
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