A degradation product of the antimigraine drug Sumatriptan. Sumatriptan succinate is a triptan drug that is used to treat migraines. It has been shown to have high specificity for 5-HT1 receptors and low affinity for 5-HT2A, 5-HT2B, or 5-HT2C receptors. Sumatriptan succinate is rapidly metabolized by monoamine oxidase type A (MAO-A) in the liver to form sumatriptan. The major metabolite of sumatriptan is N-oxide (sumatriptan N-oxide). Sumatriptan N-oxide has been shown to be less potent than sumatriptan at inhibiting the release of inflammatory substances from mast cells in vitro. Synonyms: 3-[2-(Dimethyloxidoamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide, GR 112504, Sumatriptan EP Impurity D CAS No: 212069-94-8 Molecular Formula: C14H21N3O3S Molecular Weight: 311.40 Appearance: Pale beige to light brown solid Purity: 95% (HPLC) NMR, MS, FT-IR: Conforms to reference Elemental Analysis: %C: 50.59, %H: 6.92, %N: 12.58 Water (KF): ~5% Solubility: DMSO (Slightly), Water (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
311.4
Reinheit:
95% (HPLC)
Formulierung:
Pale beige to light brown solid
CAS Nummer:
[212069-94-8]
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