| An inactive metabolite/product of Thromboxane A2 (TBXA2): a compound involved in platelet activation and aggregation in case of a wound. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis while measurement of 11-dehydro TBX2 and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion. Synonyms: 8-(1-Hydroxy-3-oxopropyl)-9,12-dihydroxy-5,10-heptadecadienoic Acid Hemiacetal, (5Z,9alpha,13E,15S)9,11,15-Trihydroxythromboxa-5,13-dien-1-oic Acid, TXB2, (5Z)-7-[(2R,3S,4S)-Tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octenyl]-2H-pyran-3-yl]-5-heptenoic Acid, (Z)-7-[(2R,3S,4S)-4,6-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]oxan-3-yl]hept-5-enoic acid, 9alpha,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid CAS No: 54397-85-2 Molecular Formula: C20H34O6 Molecular Weight: 370.48 Appearance: White to off-white solid Purity: 98% Melting Point: 85-87C Solubility: Chloroform, DMF: >50mg/ml, DMSO: >25mg/ml, Ethanol: >100mg/ml, Methyl Acetate: 10mg/ml, PBS pH 7.2: >100ug/ml Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |
