Angiocidin shows sequence similarity with proteasome components and is also being referred to as 26A proteasome regulatory subunit S5A. Angiocidin shows both matrix and cytoplasmic distribution. It binds to thrombospondin-1 and alpha2beta1 integrin, and it inhibits tumor progression and angiogenesis. Angiocidin is expressed in various types of cancer, such as hepatocellular carcinoma, prostate, lung, bladder, and melanoma cancers. Recombinant protein corresponding to human angiocidin (aa2-377), untagged, expressed in E. coli. Molecular Weight: ~50kD (SDS-PAGE) Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
