Antitumor compound. Programmed cell death inducer. Cytotoxic. Antiproliferative. p53 activator. IkappaB kinase inhibitor. NF-kappaB inhibitor. Nampt/visfatin inhibitor. Synonyms: GMX1778, (E)-1-[6-(4-Chlorophenoxy)hexyl]-2-cyano-3-(pyridin-4-yl)guanidine CAS Number: 200484-11-3 Molecular Weight: 371.9 Molecular Formula: C19H22ClN5O Solubility: DMSO, 100% ethanol or dimethylformamide Biological Activity: Inhibits Nampt activity with an IC50 of 40nM (for 1uM of enzyme). 044664 was dissolved in DMSO. Appearance: Supplied as a white to off-white solid. Purity: 98% (HPLC & NMR) Storage and Stability: Store at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
371.9
Reinheit:
98% (HPLC & NMR)
Formulierung:
Supplied as a white to off-white solid.
CAS Nummer:
[200484-11-3]
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