Cell permeable steroidal alkaloid. Specific sonic hedgehog signaling (Shh) pathway inhibitor. Directly interacts/inhibits Smo (smoothened). Teratogenic and antitumor compound. Inhibits tumor cell growth and progression. Shows selective activity against Shh-dependent tumors. Blocks abnormal cell growth associated with oncogenic mutations of Ptch and Smo in fibroblasts. Arrests cell cycle at G0/G1. Apoptosis inducer. Synonyms: 11-Deoxyjervine, 11-Deoxojervine, HSDB 3505 CAS Number: 4449-51-8 Source: Veratrum californicum Molecular Weight: 411.6 Molecular Formula: C27H41NO2 Solubility: Ethanol, methanol, DMF or DMSO. Insoluble in water. Appearance: Supplied as a white to off-white solid. Purity: 98% Storage and Stability: Store at 4C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
411.6
Reinheit:
98%
Formulierung:
Supplied as a white to off-white solid.
CAS Nummer:
[4449-51-8]
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
