Nampt/visfatin inhibitor. Inhibitor of NAD+ biosynthesis. Inhibits the enzyme/substrate complex and the free enzyme (Ki = 0.4nM and Ki = 0.3nM, respectively). Apoptosis inducer. Autophagy inducer. Causes premature senescence. Angiogenesis inhibitor. Synonyms: K 22.175, FK866, APO866, WK175, N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2E-propenamide CAS Number: 658084-64-1 Molecular Weight: 391.5 Molecular Formula: C24H29N3O2 Solubility: 100% ethanol, dimethylformamide (40mg/ml) or DMSO (25mg/ml), sparingly soluble in aqueous buffers Appearance: Supplied as a white to yellow solid. (Tends to easily liquefy.) Purity: 98% (NMR) Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
391.5
Reinheit:
98% (NMR)
Formulierung:
Supplied as a white to yellow solid.
CAS Nummer:
[658084-64-1]
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