GANT61 is a cell-permeable hexahydropyrimidine compound. A Hedgehog (Hh) signaling pathway antagonist. Inhibits Hh signaling downstream of Smo and Sufu at the level of Gli (IC50 = 5uM). GANT61 has also been shown to inhibit the in vitro proliferation of PANC1 and 22Rv1 cells which have elevated GLi11 levels and prevent the development of 22Rv1 tumors in mice. Synonyms: NSC 136476, 2,2-((Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl)bis(methylene))bis(N,N-dimethyl)-benzenamine CAS Number: 500579-04-4 Molecular Weight: 429.6 Molecular Formula: C27H35N5 Solubility: DMSO or ethanol Appearance: Supplied as a white to off-white solid. Purity: 98% Storage and Stability: Store at -20C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
429.6
Reinheit:
98%
Formulierung:
Supplied as a white to off-white solid.
CAS Nummer:
[500579-04-4]
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
