Water-soluble, slow-releasing hydrogen sulfide (H2S) donor. Exhibits vasodilator and antihypertensive activity. Anti-inflammatory. Inhibits LPS-induced release of proinflammatory mediators (IL-1beta, IL-6, TNF-alpha, nitric oxide (NO) and PGE2) and increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-kappaB, ATF-2 and HSP27 dependent pathways. Causes stomatal opening and reduces nitric oxide accumulation in plants. Oxidative stress-induced cell death inhibitor. Shows novel anti-cancer effects in vitro and in vivo. Anti-thrombotic via p-selectin dependent mechanism. Synonyms: 4-Methoxyphenyl(morpholino)phosphinodithioate morpholinium salt CAS Number: 106740-09-4 Molecular Weight: 375.5 Molecular Formula: C11H16NO2PS2C4H9NO Solubility: DMSO or water Appearance: Supplied as a white solid. Purity: 95% (NMR) Method for Determining Identity: Proton NMR Storage and Stability: May be stored at 4C for short-term only. Protect from light and moisture. Stable for 12 months after receipt when stored at -20C. Store solutions at -20C in the dark. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
375.5
Reinheit:
95% (NMR)
Formulierung:
Supplied as a white solid.
CAS Nummer:
[106740-09-4]
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