K-252a is an antibiotic, PKC, PKA and PKG inhibitor. Shows neurotropic activity by inducing neurite outgrowth. Highly potent cell permeable CaM kinase and phosphorylase inhibitor. Tyrosine protein kinase inhibitor of the TRK family. Antiproliferative and apoptosis inducer. Cell cycle arrest inducer. Potential drug for psoriasis treatment. Source: Isolated from Nonomuraea longicatena chiba Synonyms: SF 2370, Antibiotic K 252a, Antibiotic SF 2370 CAS Number: 99533-80-9 Molecular Weight: 467.47 Molecular Formula: C27H21N3O5 Solubility: DMSO, methanol, methylene chloride, ethyl acetate, acetone. Insoluble in water. Appearance: Supplied as a white to off-white powder. Purity: 98% (HPLC) Storage and Stability: Store short term at 4C. Keep cool and dry, and protect from light. For long term storage, store solutions at -20C in the dark. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
467.47
Reinheit:
98% (HPLC)
Formulierung:
Supplied as a white to off-white powder.
CAS Nummer:
[99533-80-9]
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