Antibiotic [1]. High affinity ionophore for monovalent cations such as H+, K+, Na+, Pb2+ [2, 3, 4, 7, 10]. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity [3, 6]. Disrupts membrane potential of mitochondria [2]. NLRP3/NALP3 activator. Signals through pannexin-1 to induce caspase-1 maturation and IL-1beta processing and release [5, 8, 11, 12]. Autophagy modulator [13] Source: Isolated from Streptomyces hygroscopicus CAS No: 28643-80-3 Molecular Formula: C40H67O11Na Molecular Weight: 74.94 Purity (HPLC): 98% Appearance: White to off-white powder Solubility: Soluble in methanol, ethanol, dichlormethane or ethyl acetate. Insoluble in water. Storage and Stability: Store at -20C in the dark. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
746.9
CAS Nummer:
[28643-80-3]
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