Cell permeable smoothened (Smo) agonist. Shown to induce Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Synonyms: 3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[3-(4-pyridinyl)benzyl]-1-benzothiophene-2-carboxamide, Smoothened Agonist CAS Number: 912545-86-9 Molecular Weight: 490.1 Molecular Formula: C28H28ClN3OS Solubility: DMSO, sparingly soluble in water (acidification with HCl increases water solubility). Method for Determining Identity: Proton NMR Appearance: Supplied as an off-white to light yellow powder. Purity: 98% (NMR) Storage and Stability: Store at -20C. Protect from light. Store solutions at -20C in the dark. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
490.1
Reinheit:
98% (NMR)
Formulierung:
Supplied as an off-white to light yellow powder.
CAS Nummer:
[912545-86-9]
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
