Splitomicin (Splitomycin, 1,2-Dihydro-3H-naphthopyran-3-one, 1-Naphthalen propanoic acid), CAS [[5690-03-9]]

Produktübersicht

• Artikelname: Splitomicin (Splitomycin, 1,2-Dihydro-3H-naphthopyran-3-one, 1-Naphthalen propanoic acid), CAS [[5690-03-9]]
• Artikelnummer: USB-045308
• Hersteller Artikelnummer: 045308
• Alternativnummer: USB-045308-1,USB-045308-5,USB-045308-25
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

Potent cell permeable and selective inhibitor of yeast NAD+-dependent histone deacetylase (HDAC) Sir2p. Displays higher activity in vivo than in vitro. Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket. Shown to have diverse effects also in mammalian cells. Synonyms: Splitomycin, 1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one, 1-Naphthalen propanoic acid CAS Number: 5690-03-9 Molecular Weight: 198.2 Molecular Formula: C13H10O2 Solubility: Methanol, ethanol or DMSO. Method for Determining Identity: Proton NMR Appearance: Supplied as a white to off-white solid. Purity: 98% (NMR) Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.

Produkteigenschaften

• Molekulargewicht: 198.2
• Reinheit: 98% (NMR)
• Formulierung: Supplied as a white to off-white solid.
• CAS Nummer: [5690-03-9]