Antibiotic Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells Mutagenic. Potent alkylating agent. Potent DNA methylating agent Nitric oxide (NO) donor. Vasorelaxant. Cytotoxic to cells that express GLUT2 glucose transporter. O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (O-GlcNAcase) inhibitor. Genotoxic. Induces DNA damage. Produces DNA strand breaks. Cell death inducer. Antineoplastic. Anti-cancer agent used in chemotherapy. Induces cell cylce arrest at G2. Synonyms: 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose, Streptozocin, STZ, NSC 85998, Antibiotic U9889, Zanosar CAS Number: 18883-66-4 Molecular Weight: 265.2 Molecular Formula: C8H15N3O7 Solubility: Water or ethanol. Method for Determining Identity: UV and IR Appearance: Supplied as an off-white to pale yellow powder. Purity: 98% (HPLC) 75% (alpha anomer) Note: Once the compound is in solution it spontaneously releases NO gas at room temperature. We recommend to prepare fresh solutions immediately before use. Storage and Stability: Store at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Molekulargewicht:
265.2
Reinheit:
98% (HPLC)
Formulierung:
Supplied as an off-white to pale yellow powder.
CAS Nummer:
[18883-66-4]
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