Antibiotic. Potent anti-neutrophil agent with cardioprotective effects. mTOR, DNA-PK, phosphatidylinositol 4-kinases, myosin light chain kinase (MLCK) and mitogen-activated protein kinase (MAPK) inhibitor at high concentrations. Potent cell permeable and selective inhibitor of phosphatidyl-inositol 3-kinase (PI3K). Antitumor compound. Radiosensitizing agent. Adipogenesis inhibitor. Angiogenesis inhibitor. Autophagy inhibitor. DNA repair, receptor-mediated endocytosis and cell proliferation inhibitor. Potentiates the LPS-induced nitric oxide (NO) production from macrophages. Induces in vivo Alzheimer-like hyperphosphorylation in tau. Polo-like kinase family inhibitor. Synonyms: KY 12420, BRN 0067676, NSC 627609, Antibiotic SL-2052 CAS Number: 19545-26-7 Source: Penicillium sp. Molecular Weight: 428.4 Molecular Formula: C23H24O8 Solubility: DMSO, methanol, ethanol or chloroform. Slightly soluble in water. Appearance: Supplied as a white to off-white solid. Purity: 98% (HPLC) Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
428.4
Reinheit:
98% (HPLC)
Formulierung:
Supplied as a white to off-white solid.
CAS Nummer:
[19545-26-7]
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
