Creatine Kinase MB (CK-MB, CKMB), CAS [[9001-15-4]]
Artikelnummer:
USB-045774
Hersteller Artikelnummer:
045774
Alternativnummer:
USB-045774-100
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Human Creatine Kinase is one of the most important myocardial markers (in spite of not being altogether cardiac-specific), with well-established roles in confirming acute myocardial infarction (AMI). It can also used for monitoring reperfusion during thrombolytic therapy following AMI. Testing is performed when the total Human Creatine Phosphokinase (CPK) level is elevated. Isoenzyme testing can help differentiate the source of the damaged tissue. Human CPK enzyme consists of two subunits, which can be either B (brain type) or M (muscle type). Three different isoenzymes: Creatine Kinase MM, BB, and MB isoenzymes exist. Activity: > 1000U/ml Unit Definition: One unit will catalyze the transphosphorylation of one micromole of phosphate from creatine phosphate to ADP per minute at 37C. Protein: >10mg protein/mL (Coomassie) Specific Activity: Reported in U/mg protein Isoenzyme Content: CK-MB: > 99% CK-MM: < 1.0% CK-BB: < 1.0% Contaminants: GOT/AST: <1% LDH: <1% Form: Supplied in as a liquid in 0.01M Tris-succinate, pH 7.0, 2mM DTT, 2mM EDTA, 175mM sodium chloride, 50% glycerol. No preservatives added. Purity: Purified (Control Grade) Applications: Suitable for use as a control or calibrator. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing. Store at -20C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Nummer:
[9001-15-4]
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