Casein Kinase 2 beta, Recombinant, Human, aa1-215
Artikelnummer:
USB-045994
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| Artikelname: | Casein Kinase 2 beta, Recombinant, Human, aa1-215 |
| Artikelnummer: | USB-045994 |
| Hersteller Artikelnummer: | 045994 |
| Alternativnummer: | USB-045994-10,USB-045994-20,USB-045994-50,USB-045994-100,USB-045994-250 |
| Hersteller: | US Biological |
| Kategorie: | Molekularbiologie |
| Casein Kinase 2 (CK2, also called PKCK2) is a ubiquitous Ser/Thr kinase expressed in all eukaryotes. CK2 is a tetramer composed of two catalytic kinase domains, alpha subunits, and two identical regulatory beta subunits. It has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm, and other cellular processes. The beta subunit itself does not have kinase activity, but confers stability to the CK2 alpha subunit and is involved in activity and substrate specificity. Recombinant human CK2beta was expressed in E. coli and purified by using conventional chromatography techniques. Recombinant protein corresponding to aa1-215 from human Casein Kinase 2 beta, expressed in E.coli. Swiss/Uniprot: P67870 Molecular Weight: ~24.9kD (215aa) Amino Acid Sequence: MSSSEEVSWI SWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPHYRQAL DMILDLEPDE ELEDNPNQSD LIEQAAEMLY GLIHARYILT NRGIAQMLEK YQQGDFGYCP RVYCENQPML PIGLSDIPGE AMVKLYCPKC MDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPA NQFVPRLYGF KIHPMAYQLQ LQAASNFKSP VKTIR Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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