CD9, Recombinant, Human, His-Tag, aa112-195

Produktübersicht

• Artikelname: CD9, Recombinant, Human, His-Tag, aa112-195
• Artikelnummer: USB-046010
• Hersteller Artikelnummer: 046010
• Alternativnummer: USB-046010-20,USB-046010-100
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

CD9, also known as TSPAN-29, is a member of tetraspanin family. It is found on the surface of exosomes. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. It seems CD9 has a varying role in different types of cancers. The over expression of CD9 was shown to decrease metastasis in certain types of melanoma, breast, lung, pancreas and colon carcinomas. However in other studies, CD9 has been shown to increase migration or be highly expressed in metastatic cancers in various cell lines such as lung cancer, scirrhous-type gastric cancer, hepatocellular carcinoma, acute lymphoblastic leukemia and breast cancer. Recombinant human CD9, fused to His-Tag at C-terminal, was expressed in HEK293 cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa112-195 from human CD9, fused to His-Tag at C-terminal, expressed in HEK293. Molecular Weight: ~10.7kD (93aa) Amino Acid Sequence: SHKDEVI KEVQEFYKDT YNKLKTKDEP QRETLKAIHY ALNCCGLAGG VEQFISDICP KKDVLETFTV KSCPDAIKEV FDNKFHI Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 10.7
• NCBI: 001760
• UniProt: P21926
• Reinheit: 90% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL).
• Formulierung: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.