MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer. Synonyms: 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide, MDV3100, MDV-3100 CAS Number: 915087-33-1 Molecular Formula: C21H16F4N4O2S Molecular Weight: 464.44 Appearance: White to off-white crystalline powder Purity (HPLC): 98% Melting Point: 198-200C Solubility: DMSO (Slightly), Methanol (Slightly)
Molekulargewicht:
464.44
Reinheit:
98%
Formulierung:
White to off-white crystalline powder
CAS Nummer:
[915087-33-1]
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