FSTL1 (Follistatin-like Protein 1, Follistatin-related Protein 1, FRP) BioAssay(TM) ELISA Kit, Human
Artikelnummer:
USB-143841
Hersteller Artikelnummer:
143841
Alternativnummer:
USB-143841-96
Hersteller:
US Biological
Kategorie:
Kits/Assays
Sandwich ELISA quantitative detection kit for Human FSTL1 in cell culture supernates, serum and plasma (heparin, EDTA). Follistatin-related protein 1, also called FSTL1 or FRP is a protein that in humans is encoded by the FSTL1 gene. FSTL1 gene is mapped to chromosome 3q13.33 based on an alignment of FSTL1 sequence with the genomic sequence (GRCh37). This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis. This gene may modulate the action of some growth factors on cell proliferation and differentiation. It was suggested that fibroblast-secreted FSTL1 acts on macrophages to increase TNF and IL1B production and IL6 activity. Assay Range: 312pg/ml-20,000pg/ml Sensitivity: < 10 pg/ml Crossreactivity: There is no detectable cross-reactivity with other relevant proteins. Uniprot ID: Q12841 Entrez Gene ID: 11167 Kit Components: 96-well plate pre-coated with anti-FSTL1, Human Lyophilized recombinant FSTL1, Human standard, 10ng/tube, 2Ea USB Cat No Kit Component 143696 Avidin-Biotin-Peroxidase Complex (ABC), 130ul (1:100 dilution) 143697 Sample diluent buffer, 30ml 143698 Antibody diluent buffer, 12ml 143699 ABC diluent buffer, 12ml 143700 TMB color developing agent, 10ml 143701 TMB stop solution, 10ml Storage and Handling: Store at 4C for 6 months, at -20C for 12 months. Avoid multiple freeze-thaw cycles.
