Entacapone ((2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide), CAS [[130929-57-6]]

Produktübersicht

• Artikelname: Entacapone ((2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide), CAS [[130929-57-6]]
• Artikelnummer: USB-145673
• Hersteller Artikelnummer: 145673
• Alternativnummer: USB-145673-10,USB-145673-50
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

Potent catechol O-methyltransferase (COMT) inhibitor (IC50 values are 14.3, 20.1 and 73.3nm for rat liver soluble COMT, total COMT and membrane-bound COMT respectively). Increases bioavailability of levodopa when given as an adjunct therapy for Parkinsons disease. Inhibits alpha-synuclein aggregation in an in vitro assay, blocks alpha-synuclein-induced cell death in PC-12 cells. Formula: C14H15N3O5 Solubility: DMSO (~100mM), Ethanol (~10mM) Molecular Weight: ~305.29 Storage and Stability: Store at RT. Stable for 12 months.

Produkteigenschaften

• Molekulargewicht: 305.29
• Reinheit: ~99% (HPLC)
• Formulierung: Supplied as a yellow solid.
• CAS Nummer: [130929-57-6]