AP3B2 (AP-3 Complex Subunit beta-2, Adapter-related Protein Complex 3 Subunit beta-2, Adaptor Protein Complex AP-3 Subunit beta-2, Beta-3B-adaptin, Clathrin Assembly Protein Complex 3 beta-2 large Chain, Neuron-specific Vesicle Co

Artikelnummer: USB-146866
Artikelname: AP3B2 (AP-3 Complex Subunit beta-2, Adapter-related Protein Complex 3 Subunit beta-2, Adaptor Protein Complex AP-3 Subunit beta-2, Beta-3B-adaptin, Clathrin Assembly Protein Complex 3 beta-2 large Chain, Neuron-specific Vesicle Co
Artikelnummer: USB-146866
Hersteller Artikelnummer: 146866
Alternativnummer: USB-146866-100
Hersteller: US Biological
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IF, IHC, WB
Immunogen: Synthetic peptide corresponding to 18aa from near the N-terminus of human AP3B2.
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores. Applications: Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1-2ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Rat Brain Tissue Lysate Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Reinheit: Purified by immunoaffinity chromatography.
Formulierung: Supplied as a liquid in PBS, 0.02% sodium azide.