CEBPD (C/EBP related protein 3, CCAAT/enhancer binding protein delta, CEBP D, CEBPD, CELF, Crp 3, Crp3, NF IL6 beta, Nuclear factor NF IL6 beta), Rabbit

Produktübersicht

• Artikelname: CEBPD (C/EBP related protein 3, CCAAT/enhancer binding protein delta, CEBP D, CEBPD, CELF, Crp 3, Crp3, NF IL6 beta, Nuclear factor NF IL6 beta), Rabbit
• Artikelnummer: USB-168094
• Hersteller Artikelnummer: 168094
• Alternativnummer: USB-168094-100
• Hersteller: US Biological
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IP, WB
• Immunogen: Recombinant protein corresponding to mouse C/EBP at N-terminus.

Produktbeschreibung

C/EBP proteins are DNA-binding proteins that are important transcriptional activators in the regulation of genes involved in immune and inflammatory responses and may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages. Members of the C/EBP transcription factor family are related by a high degree of aa sequence identity to the basic leucine zipper DNA-binding domain and show distinct but overlapping patterns of tissue and stage restricted expression. Osada et al. identified the consensus binding site for the family as RTTGCGYAAY (R=A or G, and Y=C or T). Phosphorylation of C/EBPd may increase binding activity, whereas phosphorylation of the a and b family members may decrease binding affinity. C/EBPd is a nuclear protein that binds DNA as a dimer and can form stable heterodimers with all other C/EBP family members. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: ELISA: 1:4000-1:9000 Western Blot: 1:1000-1:15,000 Immunoprecipitation: 0.8-1.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Produkteigenschaften

• Reinheit: Purified by immunoaffinity chromatography.
• Formulierung: Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.