Calphostin C (UCN 1028C, PKF115-584, Cal-C), CAS [[121263-19-2]]

Produktübersicht

• Artikelname: Calphostin C (UCN 1028C, PKF115-584, Cal-C), CAS [[121263-19-2]]
• Artikelnummer: USB-207099
• Hersteller Artikelnummer: 207099
• Alternativnummer: USB-207099-100,USB-207099-1
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

Potent and highly specific cell permeable protein kinase C (PKC) inhibitor. The inhibition of PKC is light-dependent. PKA, PKG, DAG kinase, phospholipase D1 and D2, myosin light chain kinase and c-Src inhibitor. Anticancer compound. Inhibits cell proliferation and strongly induces apoptosis in vitro. Inducer of endoplasmic reticulum ER-stress. Shown to directly and potently block L-type Ca channels. Calphostin C specifically inhibits contraction-stimulated glucose transport but not insulin-stimulated glucose transport in skeletal muscle. Wnt/beta-catenin/lef-1 signaling inhibitor. beta-catenin/TCF antagonist. Inhibits Wnt-activated genes in a dose-dependent fashion. Source: Cladosporium cladosporioides sp. Synonyms: UCN 1028C, PKF115-584, Cal-C Molecular Formula: C44H38O14 Molecular Weight: ~790.8 Purity (HPLC): 95% Appearance: Dark red to brown solid Solubility: Ehanol, Methanol, DMSO or DMF. Poorly soluble in Water. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 6 months after receipt at -20C. Reconstitute and aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 790.8
• Reinheit: 95% (HPLC)
• Formulierung: Dark red to brown solid
• CAS Nummer: [121263-19-2]