Antibiotic. Antitumor compound. Powerful, selective inhibitor of nucleic acid synthesis in vitro. Potent hypoxia-inducible factor 1 (HIF-1) DNA binding activity inhibitor. Apoptosis inducer. Antibacterial, antifungal and antiviral. CAS Number: 512-64-1 Alternate Names: Echinomycin, Actinoleukin, Antibiotic 1491, Antibiotic 59266, Antibiotic X 948, Antibiotic X 53III, N-(2-Quinoxalinylcarbonyl)-O-[N-(2-quinoxalinylcarbonyl)-D-seryl-L-alanyl-3-mercapto-N,S-dimethylcysteinyl-N-methyl-L-valyl]-D-seryl-L-alanyl-N-methylcysteinyl-N-methyl L-valine (81)-lactone cyclic (37)-thioester Source: Streptomyces echinatus (DSM 40013) Molecular Formula: C51H64N12O12S2 Solubility: Acetone, DMSO (50mg/ml), methanol, dichloromethane or ethyl acetate. Method for Determining Identity: Proton NMR Molecular Weight: 1101.3 Appearance: Supplied as a white to off-white solid. Purity: 98% (HPLC) Storage and Stability: Store at -20C under inert atmosphere. Hygroscopic. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Molekulargewicht:
1101.3
Reinheit:
98% (HPLC)
Formulierung:
Supplied as a white to off-white solid. Contains traces of water.
CAS Nummer:
[512-64-1]
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