| Mycotoxin. Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP, ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro. CAS Number: 118974-02-0 Alternate Names: FTC, Tryptoquivaline, (5aS,12S,14aS)-1,2,3,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1,2:4,5]pyrazino[1,2:1,6]pyrido[3,4-b]indole-5,14-dione Source: Aspergillus fumigatus Molecular Formula: C22H25N3O3 Solubility: DMSO, methanol, acetone, DMF or chloroform. A concentration of 1mg/ml is recommended for stock solutions. Molecular Weight: 379.5 Method for Determining Identity: Proton NMR Purity: 98% (HPLC) Appearance: Supplied as a white to light brown powder. Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. |
