Leucettine L41 ((5Z)-5-(1,3-Benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4one), CAS [[1112978-84-3]]

Produktübersicht

• Artikelname: Leucettine L41 ((5Z)-5-(1,3-Benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4one), CAS [[1112978-84-3]]
• Artikelnummer: USB-207259
• Hersteller Artikelnummer: 207259
• Alternativnummer: USB-207259-1,USB-207259-5,USB-207259-25
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Tools to study and modulate pre-RNA splicing. Potential compound for Alzheimers disease and diseases involving abnormal pre-mRNA splicing. Potential compound to study Down syndrome (inhibition of DYRK1A). Neuroprotective against glutamate-induced cell death. Formula: C17H13N3O3 Solubility: DMSO or ethanol Molecular Weight: ~307.3 Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with DMSO or ethanol. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 307.3
• Reinheit: ~98% (NMR)
• Formulierung: Supplied as a beige solid.
• CAS Nummer: [1112978-84-3]