Offensive principle of the so-called headache tree. Causes a painful cold sensation. Selective TRPA1 activator. Weak TRPM8 activator. Releases CGRP (calcitoningene-related peptide) after TRPA1 activation which leads to activation of trigeminovascular pathways and CGRP-mediated neurogenic vasodilatation relevant to produce headache/migraine. Synonyms: (1R, 5S)-4-Methyl-1-propan-2-ylbicyclo(3.1.0)hex-3-en-2-one, (1R,5S)-(-)-3-Thujen-2-one, Thujen-2-one, Thujenone CAS Number: 546-78-1 Source: Umbellularia californica Nutt Molecular Formula: C10H14O Solubility: DMSO or ethanol Molecular Weight: 150.2 Appearance: Supplied as a colorless oil. Purity: 98% (HPLC) Method for Determining Identity: Proton NMR Irritant: Umbellulone is a headache-inducing monoterpene ketone. Can induce headache when inhaling. Caution should be taken when dealing with this substance. Storage and Stability: May be stored at 4C for short-term only. Stable for 12 months after receipt when stored at -20C. Keep cool and dry. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Molekulargewicht:
150.2
Reinheit:
98% (HPLC)
Formulierung:
Supplied as a colorless oil.
CAS Nummer:
[546-78-1]
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