H-FABP, also known as heart type fatty-acid binding protein, and FABP3. H-FABP belongs to the FABP family, and is a 14kD cytosolic non-enzymatic protein involved in the uptake, transport and metabolism of fatty acids. H-FABP also has a role in cell proliferation and is a candidate tumor suppressor gene in breast cancer. H-FABP was initially purified from the heart muscle, but has since been found to have a widespread tissue distribution, with highest concentration in cardiac and skeletal muscle. H-FABP has been implicated in neurodegenerative disorders, including Down syndrome and Alzheimers disease, and is a specific and sensitive biomarker for acute myocardial infarctions. Applications: Suitable for use in Immunoassay, ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
