CD134 (OX-40, Tumor Necrosis Factor Receptor Superfamily Member 4, TNFRSF4), IgG1, Clone: [14L152], Rat, Monoclonal

Produktübersicht

• Artikelname: CD134 (OX-40, Tumor Necrosis Factor Receptor Superfamily Member 4, TNFRSF4), IgG1, Clone: [14L152], Rat, Monoclonal
• Artikelnummer: USB-216248
• Hersteller Artikelnummer: 216248
• Alternativnummer: USB-216248-1
• Hersteller: US Biological
• Wirt: Rat
• Kategorie: Antikörper
• Applikation: FC, IHC
• Immunogen: Recombinant protein corresponding to mouse CD134

Produktbeschreibung

CD134 is a type I integral membrane protein, also known as OX-40, ACT35, and tumor necrosis factor receptor superfamily member 4 (TNFRSF4). This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX-40 receptor binds to the OX-40 ligand (CD252) to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, which implies that these interactions are important in the pathogenesis of some autoimmune diseases. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry, and Stimulation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Endotoxin: <0.002EU/ug Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [14L152]
• Isotyp: IgG1
• Reinheit: Purified by Protein G affinity chromatography from culture supernatant.
• Formulierung: Supplied as a lyophilized powder in PBS. No preservative added. Reconstitute with sterile PBS.