Flumazenil (GABAA Receptor Antagonist, Flumazenil, Ro 15-1788), CAS [[78755-81-4]]

Produktübersicht

• Artikelname: Flumazenil (GABAA Receptor Antagonist, Flumazenil, Ro 15-1788), CAS [[78755-81-4]]
• Artikelnummer: USB-217359
• Hersteller Artikelnummer: 217359
• Alternativnummer: USB-217359-10
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

A competitive blocker of benzodiazepine activation of inhibitory GABAergic synpases (ID50 = 200ug/kg/i.p). Binds to the benzodiazepine site of GABAA receptors. Enhances GABAA-receptor mediated currents and antagonizes the enhancing effects of benzodiapine agonist flurazepam. Exhibits fast association and dissociation from the benzodiazepine binding site. Permeates the blood brain barrier, however, the level of uptake may depend on efflux effects of p-glycogprotein transporter. Synonyms: GABAA Receptor Antagonist, Flumazenil, Ro 15-1788, 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester CAS No: 78755-81-4 Molecular Formula: C15H14FN3O3 Solubility: DMSO Primary Target: GABA-A Purity: 99% (HPLC) Appearance: White solid. Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Reinheit: 99% (HPLC)
• Formulierung: White solid.
• CAS Nummer: [78755-81-4]