LY-404,039 ((1R,4S,5S,6S)-4-[[(2S)-2-Amino-4-(methylthio)-1-oxobutyl]amino]-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic Acid 2,2-dioxide), CAS [[635318-55-7]]

Produktübersicht

• Artikelname: LY-404,039 ((1R,4S,5S,6S)-4-[[(2S)-2-Amino-4-(methylthio)-1-oxobutyl]amino]-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic Acid 2,2-dioxide), CAS [[635318-55-7]]
• Artikelnummer: USB-217527
• Hersteller Artikelnummer: 217527
• Alternativnummer: USB-217527-5
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

A highly selective and potent agonist for recombinant human mGlu2 and mGlu3 receptors (Ki = 149nM and 92nM, respectively) and for rat neurons mGlu2/3 receptors (Ki = 88nM). Negligible interactions with other mGlu receptors and ionotropic glutamate receptors, glutamate transporter subtypes, monoamine and other receptors. Widely used for investigating neuropsychiatric disorders in animal models and developing potential treatment for human mental disorders, such as schizophrenia. CAS Number: 635318-55-7 Formula: C7H9NO6S Solubility: DMSO or dilute NaOH Primary Target: mGlu2 & mGlu3 Primary Target Ki: 149nM and 92nM for human mGlu2 and mGlu3, respectively. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Reinheit: 98% (NMR)
• Formulierung: Supplied as a white powder.
• CAS Nummer: [635318-55-7]