A benzazepine derivative that acts as a selective Dopamine D1/D5 receptor partial agonist. Examination of the isomers in several in vitro and in vivo tests for both central and peripheral dopaminergic activity revealed that activity resided almost exclusively in the R isomer. The results suggest that the properly oriented 1-phenyl substituent of 1 is important for dopamine-like activity. Reported to have stimulant and anorectic effects. Synonyms: Dopamine D1/D5 Receptor Partial Agonist, (R)-SKF-38393 Hydrochloride, SKF-38393, SKF38393, SKF 38393 CAS Number: 81702-42-3 Molecular Formula: C16H17NO2HCl Solubility: H2O Primary Target: D1 Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Reinheit:
98% (HPLC)
Formulierung:
Supplied as a white solid.
CAS Nummer:
[81702-42-3]
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