An arylcarboxamide that acts as a potent and selective sphingosine-1-phosphate receptor 4 (S1P4) antagonist (IC50=25nM), among a panel of five S1P receptors. It is shown to inhibit other S1P isoforms only at much higher concentrations (IC50 = 6.4uM, 3.9uM, 5.5uM, and 25uM for S1P1, S1P2, S1P5, and S1P3 (95% inhibition), respectively). Synonyms: N-(4-(Aminomethyl)-2,6-dimethylphenyl)-5-(2,5-dichlorophenyl)furan-2-carboxamide CAS No: 1314212-39-9 Molecular Formula: C20H18Cl2N2O2 Molecular Weight: 389.28 Purity: 97% Form: Supplied as a white powder. Solubility: DMSO: 20mg/mL, clear Storage and Stability: Store at 4C under inert atmosphere. Light sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
389.28
CAS Nummer:
[1314212-39-9]
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