A cell-permeable pyrroloquinoxaline compound that acts as a reversible SIRT1 activator (10uM causes ~2.3-fold fluorescent enhancement in a fluorescent assay using hrSIRT1) and enhances fat mobilization in fully differentiated 3T3L1 fibroblasts. Shown to inhibit LPS-induced TNF-a release in THP-1 cells by ~10-fold more potent than resveratrol. Synonyms: 3-(Benzenesulfonyl)-1-(4-fluorophenyl)pyrrolo[4,5-b]quinoxalin-2- amine, SIRT1 Activator II CAS No: 374922-43-7 Molecular Formula: C22H15FN4O2S Molecular Weight: 418.4 Solubility: DMF, DMSO, DMSO:PBS, pH 7.2, (1:3): 0.25 mg/ml Appearance: Supplied as an off-white powder. Purity: 95% Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
418.4
CAS Nummer:
[374922-43-7]
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
