Fluorexon is a novel fluorogenic probe that can be used as an optical sensor to measure the activity of polymerase chain reactions. Fluorexon has been shown to localize in mitochondria and to induce cytotoxicity in cancer cells. The drug also induces apoptosis through mitochondrial membrane potential depolarization and oxidative injury. This compound has demonstrated acute toxicities, but it is not known if these are due to its effects on drug transporters or its ability to increase cytosolic calcium. Synonyms: Fluorexon, Fluorescein-bis(methyliminodiacetic acid), Bis[N,N-bis(carboxymethyl)aminomethyl]fluorescein, Complexone, Oftasceinum, Oftasceina, Oftasceine, NSC 298193, 2,2,2,2-(((3,6-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9-xanthene]-2,7-diyl)bis(methylene))bis(azanetriyl))tetraacetic acid CAS No: 1461-15-0 Molecular Formula: C30H26N2O13 Molecular Weight: 622.54 Appearance: Orange to orange-yellow powder Solubility (1M NaOH, 50mg/ml): Orange to brown clear solution Absorbance (1N NaOH, 492-497nm): 1000 Storage and Stability: Store at RT. Stable for 12 months after receipt.
Molekulargewicht:
622.54
CAS Nummer:
[1461-15-0]
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
