A phospholipid drug with antineoplastic and antiprotozoal/antifungal properties, also acts as an Akt inhibitor, and under investigation as a potential therapy against HIV infection. Used for the treatment of visceral and cutaneous leishmaniasis. Active against metronidazole-resistant and -susceptible strains of Trichomonas vaginalis.1 HePC induces an apoptosis-like cell death in the unicellular protozoan parasite Leishmania donovani, the causative agent of leishmaniasis. Hexadecylphosphocholine (HePC) is an effective apoptosis inducer. Originally developed as an anticancer drug and has been used for treatment of skin metastases of breast cancer. The anti-tumor activity of HePC has been linked with its capacity to induce apoptosis in numerous tumor cell lines. Due to its amphiphilic behavior, HePC accumulates at the cell membrane, affecting membrane fluidity and triggering the apoptotic cell death. Synonyms: 2-[[(Hexadecyloxy)hydroxyphosphinyl]oxy]-N,N,N-trimethylethanaminium, Hexadecylphosphocholine, Hexadecylphosphorylcholine, Miltefosine, Miltex, n-Hexadecylphosphocholine, 1-Hexadecylphosphorylcholine, Choline Hexadecyl Phosphate, HePC+ CAS No: 58066-85-6 Molecular Formula: C21H46NO4P Molecular Weight: 407.57 Purity: 98% Appearance: White to off-white powder Identity (IR): Conforms to structure Solubility (H2O): Soluble to 10mg/ml, clear, colorless Storage and Stability: Powder may be stored at 4C. Stable for 6 months after receipt. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Molekulargewicht:
407.57
Reinheit:
98%
Formulierung:
White to off-white powder
CAS Nummer:
[58066-85-6]
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
