Protamine Sulfate is a small cationic protein that binds and precipitates DNA. It may be used for the removal of DNA from protein samples or the purification of DNA binding proteins. Protamine Sulfate has antibacterial properties. Protamine sulfate is a highly cationic peptide binding to heparin. It binds to and precipitates DNA, and can be used to remove DNA from protein samples. Protamine are proteins rich in cysteine and arginine. It possesses many phosphorylation sites. It is found to be localized to the sperm head. Can be used as an alternate to polybrene in retroviral-mediated gene transfer. Cell labeling with protamine sulfate complexed to ferumoxides has been used. Synonyms: Clupeine sulfate, protamine sulfate, protamine sulfate herring, protamine sulfate, salmon milt, salmine, salmine sulfate CAS Number: 53597-25-4 Appearance: White to almost white hygroscopic powder Solubility: Hot water: 6M HCl 25mg/ml Activity: 100 units of Heparin sodium/mg Total Nitrogen: 21-26% (after drying) Specific Rotation ([a]D20, (C=1 in 0.1mol/L HCl): -65.0 to -85.0 Loss on Drying: 10% Bacterial Endotoxins: 7IIU/mg Storage and Stability: May be stored at RT for short-term only. Store at 4C. Stable for 6 months after receipt.
CAS Nummer:
[53597-25-4]
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