Selective antagonist of neurosteroid potentiation and direct gating of GABAA receptors. Selectively reduces the effects of 5alpha-reduced steroids compared to 5beta-reduced steroids and displays no effect on potentiation evoked by barbiturates and benzodiazepines. Attenuates 3alpha,5alpha-THP-induced loss of righting reflex and total sleep time following i.c.v administration in rats. Synonym: 17-Phenyl-(3alpha,5alpha)-androst-16-en-3-ol CAS Number: 694438-95-4 Molecular Weight: 350.54 Molecular Formula: C25H34O Solubility: DMSO to 25mM, ethanol to 50mM TLC: Rf=0.23 (Ethyl acetate:Petroleum ether [1:7]) Method for Determining Identity: Proton NMR and Mass Spectrometric Analysis Appearance: Supplied as a white solid. Purity: 99% (HPLC) Storage and Stability: Store at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
350.54
Reinheit:
99% (HPLC)
Formulierung:
Supplied as a white solid.
CAS Nummer:
[694438-95-4]
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