Inhibitor of ecto-ATPase which blocks the hydrolysis of nucleoside diphosphates and triphosphates in extracellular space. The compound inhibits NTPDase1, NTPDase 3, NTPDase 8 and NPP1and prolongs the effect of ATP on purinergic P2 receptors in environment with physiological concentrations of nucleotides. The compound has variable effectiveness as ecto-ATP inhibitor in mouse, rat, human and guineia pig tissues. Synonyms: N,N-diethyl-5-Adenylic Acid 5-anhydride with P,P-(Dibromomethylene)bis[phosphonic Acid]Sodium Salt CAS No: 1021868-83-6 Free Acid: 160928-38-1 Molecular Formula: C15H21Br2N5Na3O12P3 Molecular Weight: 785.05 Appearance: White to off-white powder Purity: 99% (HPLC) Identity (1H NMR): Conforms to reference Elemental analysis (C)/(H)/(N) (on dry basis): C,22.55 - 23.35% H:2.30 - 3.10% N:8.52 - 9.32% Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
785.05
Reinheit:
99% (HPLC)
Formulierung:
White to off-white powder
CAS Nummer:
[1021868-83-6]
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