GMQ hydrochloride is a blocker with sensitivity and blocking effects. It blocks the neurogenic inflammation induced by proton influx, which may be due to its antagonistic effect on 5-hydroxytryptamine (5-HT) receptors. GMQ hydrochloride has been shown to block the neurogenic inflammation induced by injecting substances into the skin or muscle of mice. GMQ hydrochloride also blocks the neurogenic inflammation that arises from chronic migraine, which is related to 5-HT3 receptors. Synonyms: 2-Guanidine-4-methylquinazoline hydrochloride, 4-Methyl-2-guanidino quinazoline hydrochloride, N-(4-Methyl-2-quinazolinyl)-guanidine hydrochloride, NSC 403387 hydrochloride CAS No: 5361-15-9 Molecular Formula: C10H11N5HCl Molecular Weight: 237.69 Appearance: White to off-white powder Purity: 95% (HPLC) Solubility: DMSO: 2mg/ml, clear (warmed) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Reinheit:
95% (HPLC)
Formulierung:
White to off-white powder
CAS Nummer:
[5361-15-9]
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