Potent beta3-adrenergic receptor partial agonist > 1000-fold selective over beta1- and beta2-adrenoceptors (EC50 values are 0.43, 580 and > 10000 nM for activation of cloned human beta3-, beta1- and beta2-adrenoceptors respectively). Stimulates lipolysis in rhesus adipocytes in vitro (EC50 = 3.9nM). Enhances CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs). Synonyms: 4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]benzenesulfonamide, (S)-4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]benzenesulfonamide CAS No: 159182-43-1 Molecular Formula: C30H40N4O6S Molecular Weight: 584.73 Appearance Supplied as an off-white solid. Purity: 98% Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol Storage and Stability: Store at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
584.73
Reinheit:
98%
Formulierung:
Supplied as an off-white solid.
CAS Nummer:
[159182-43-1]
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