Selective alpha7 nAChR agonist. Agonist of the alpha7 nicotinic acetylcholine receptor (Ki values are 44 and 2800 for alpha7 and 5-HT3 respectively, IC50 values are > 100 µM for alpha3beta4 and alpha1beta1deltagamma respectively, and % inhibition is < 1 and 5% for alpha4beta2 and hERG respectively). Orally active and brain penetrant. Synonyms: N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,3-dihydro-1,4-benzodioxin-6-carboxamide Fumarate CAS No: 527680-57-5 Molecular Formula: C20H24N2O7 Molecular Weight: 404.41 Appearance: White to off-white solid Purity: 99% (HPLC) Melting Point: Solubility: Water, DMSO Storage: 4C
Molekulargewicht:
404.41
Reinheit:
99% (HPLC)
Formulierung:
White to off-white solid
CAS Nummer:
[527680-57-5]
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