PNU 142633 is a very selective, high affinity 5-HT1D receptor agonist (Ki values are 6 and > 18000 nM at human 5-HT1D and 5-HT1B receptors respectively). Inhibits sympathetically-induced tachycardic responses and blocks neurogenic plasma protein extravasation in vivo. Synonyms: (1S)-1-[2-[4-[4-(Aminocarbonyl)phenyl]-1-piperazinyl]ethyl]-3,4-dihydro-N-methyl-1H-2-benzopyran-6-carboxamide CAS Number: 187665-65-2 Molecular Formula: C24H30N4O3 Molecular Weight: 422.53 Solubility: DMSO TLC: Rf = 0.54 (Chloroform:Methanol [8:2]) 1H NMR: Consistent with structure Mass Spectrum: Consistent with structure Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
422.53
Reinheit:
98%
Formulierung:
Off-white solid
CAS Nummer:
[187665-65-2]
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