A highly potent and selective mGlu8a agonist (EC50 = 31nM, a value of 100-fold lower those for mGlu1-7). Negligible activation at nMDA and kainate receptors. Exerts an amygdala mediated angiogenic-effect and evokes neuronal activities in stress-related brain areas following systemic administration in mice in vivo. A potent anticonvulsant in mice in vivo. Synonyms: 4-[(S)-Aminocarboxymethyl]-1,2-benzenedicarboxylic Acid, DCPG, (S)-3,4-Dicarboxyphenylglycine CAS Number: 201730-11-2 Molecular Formula: C10H9NO6 Molecular Weight: 239.18 Appearance: White solid Purity: 98% (HPLC) Primary Target: mGlu8a Solubility: Water, 25-100mg/ml Storage and Stability: Store at 4C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
239.18
Reinheit:
98% (HPLC)
Formulierung:
White solid
CAS Nummer:
[201730-11-2]
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