A highly potent and selective dopamine D1-like receptor antagonist with a Ki of 0.2 and 0.3nM for the D1 and D5 dopamine receptor subtypes, respectively. Also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3nM and 9.3nM respectively). Synonyms: (R)-(+)-SCH 23390 hydrochloride, (R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride CAS No: 125941-87-9 Molecular Weight: 324.24 Molecular Formula: C17H18ClNOHCl Method for Determining Identity: Proton NMR Spectroscopic and Mass Spectrometric Analysis Optical Rotation: [alpha]D = +30.8 (Concentration = 1, Solvent = DMF) Solubility: 100mM in water with gentle warming and to 50mM in ethanol Purity: 98% Appearance: White solid Storage and Stability: Desiccate at 4C
Molekulargewicht:
324.24
CAS Nummer:
[125941-87-9]
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