Dalbavancin is a drug that belongs to the class of antimicrobial agents. It is indicated for the treatment of acute bacterial skin and skin structure infections due to susceptible gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecium. Dalbavancin binds to the penicillin-binding proteins in bacterial cell walls by competitive inhibition, which prevents formation of antibiotic-inhibitor complexes with enzymes required for cell wall synthesis. This binding prevents protein synthesis and cell division, leading to cell death. Dalbavancin has been shown to be effective against human pathogens, including methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant Enterococcus faecium (VRE), Streptococcus pneumoniae, Streptococcus pyogenes, Enterobacter cloacae, Klebsie. Synonyms: 5,31-dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-beta-D-glucopyranuronosyl]-38-[[[3-(dimethylamino)propyl]amino]carbonyl]-42-O-alpha-D-mannopyranosyl-N15-methyl-ristomycin A aglycone, BI 397, A-A 1, Dalbavancin B0, MDL 63397, VER 001 CAS No: 171500-79-1 Molecular Formula: C88H100Cl2N10O28 Molecular Weight: 1816.69 Purity: 95% (mixture of A0, A1, B0, B1, B2) Appearance: White to off-white solid Melting Point: >160C (dec.) Solubility: As reported Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
1816.69
CAS Nummer:
[171500-79-1]
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