Standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ. Inhibits cell growth and induces cell death in numerous cancer cell lines, inhibits cell proliferation and viability and induces apoptosis in 4T1 mouse breast cancer cells in vitro. Exhibits antimetastatic activity. Also inhibits autophagy via a mechanism distinct from that of 3-methyladenine Synonyms: N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine Diphosphate Salt, Aralen Diphosphate, Aralen Phosphate, Arechin, Avloclor, Bemaphate, Chingamin, Chingamin Phosphate, SN 7618, Sanoquin, Tanakan CAS Number: 50-63-5 Free Base: 54-05-7 Molecular Formula: C18H32ClN3O8P2 Molecular Weight: 515.86 Appearance: White to off-white crystalline powder Purity: 98.5% Melting Point: 195-199C Loss on Drying: 2% Solubility: Water (Slightly, Heated) Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
515.86
Reinheit:
98.5%
Formulierung:
White to off-white crystalline powder
CAS Nummer:
[50-63-5]
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